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By home insurance CHUN
Sun staff writer
---------------------------------------------------------------------
Two weeks ago, the television advertisements touting the
cholesterol-lowering drug were everywhere. Their message: You cheap renters insurance your
bad cholesterol from two sources, food and family. The solution:
Take Vytorin.
Continue to 2nd paragraph Special better auto insurance The Sun The drug Vytorin is
shown.
FYI: Statins
------------
VYTORIN
* Combines Zocor (a statin) and Zetia.
* Effective in reducing LDL (bad) cholesterol levels.
* Shown in a newly-released study to be no more effective than Zocor
(or a generic statin) in reducing plaque buildup in neck arteries.
* multiple insurance quotes effects may include headache, joint pain, gas.
ZOCOR, LIPITOR, CRESTOR
* Three of many statins designed to block production of cholesterol
in the liver.
* Lowers LDL house insurance cholesterol.
* Studies show it boosts HDL (good) cholesterol, reduces artery
inflammation.
custom poker cards Side effects of statins can include aching muscles, elevated liver
enzymes.
ZETIA
* Blocks absorption of LDL cholesterol in the liver.
* Often prescribed to patients who cannot tolerate the side effects
of statins.
* Has been shown to lower LDL, but was not effective in boosting
HDL, reducing artery inflammation.
* Side effects can include muscle pain, headaches, poker shape playing cards and fever.
IF YOU TAKE VYTORIN:
* Don't stop the medication on your own.
* Talk with your doctor about what the options are.
* Consider whether a generic statin would work as well or streetwear clothes - Paul Doering, UF professor of pharmacy practice
Then came the release of a mandarin tutor chicago that was nearly poker cards years old, showing
that Vytorin, among the most widely used prescription medications, was
no better at slowing the building of plaque in your arteries than a
much cheaper, generic form of statin.
Patients who were paying $3 a pill for their prescription Vytorin were
left scratching their heads. Should they stop? Should they switch?
Paul Doering, a distinguished service professor in the department of
pharmacy practice at the University of Florida's College of Pharmacy,
has independent style definite views on Vytorin and the marketing behind it.
Behind the urgent headlines, Doering said, there is actually some good
news for consumers.
"The key issue is not a question of safety, but whether people who
have been taking this medicine have been wasting their time, effort
and money," he said. "There is no urgency for people to stop it
tomorrow, lest they die of a heart attack."
Vytorin (and a sister drug, Zetia) has been a proven money-maker for
the parent drug companies in the four years since it was introduced.
In 2006, 18 million prescriptions were written for Vytorin and 14
million for Zetia. Merck and Schering-Plough, which make the two and
split the profits, report the drugs generate annual sales of
playing cards billion.
Vytorin is actually a combination of two earlier drugs - the statin
Zocor cheap car insurance the nonstatin Zetia - that was touted as a one-two punch
that would be more effective than a statin alone. Statins inhibit the
production of cholesterol in the liver, and the nonstatin Zetia keeps
cholesterol from being absorbed in the intestine.
The makers of Lipitor, promotional playing cards statin-like drug that is also widely
advertised on television, claim it has been prescribed for 26
million Americans.
The potential market for any new cholesterol-lowering drug is huge.
According to the Centers for emo clothes Control and Prevention,
approximately a fifth of U.S. adults over 20 years of age have
elevated cholesterol, and 23 million suffer from heart disease. Heart
disease and stroke are two of the three leading causes of death.
So Doering was not surprised to hear that Vytorin's parent companies
might have delayed reporting on a study involving just 720 patients,
but one that seems to indicate their drug wasn't as effective as
advertised. "They appear to have been sitting on this data for a
couple of years while their cash registers were ringing. That raises
questions about whether they're honest and open," Doering said.
"The company is standing by its drug, but I understand a typical
doctor's office is getting 22 phone calls a day from patients asking
what they should do," he noted.
Because the research has not yet been published indie style full form, doctors
are as confused about the results as their patients are, according to
Doering. The drug companies have taken out full-page ads in newspapers
to reassure people that Vytorin is a safe and effective medication.
A Florida grandmother who was paying $100 a month for her Vytorin has
filed suit against the drug companies for misleading advertising.
The FDA announced Friday it is taking a closer look at whether any
changes need to be made to how cholesterol-lowering drugs are
regulated. The government agency estimates it will streetwear fashion another six
months to fully evaluate the data for Vytorin compared with a
generic statin.
Doering jumbo playing cards consumers need to recognize that there is a reason drug
companies promote the newest, latest formula of a medication. The
makers of Vytorin hold the patent on their new medication, while
cholesterol-lowering statins that have been around far longer are now
out of patent and available in generic form.
"Consumer Reports Best Buy Drugs" notes that Vytorin is considerably
more expensive than simvastatin, a generic form of Zocor produced by
several different pharmaceutical companies. A month's worth of Vytorin
averaged $120, while simvastatin was $40 to $75, depending on dosage,
the consumer guide reports. Most health care plans have a lower co-pay
for a generic than for brand-name drugs.
Guidelines for physicians suggest Vytorin should not be a doctor's
first choice for a patient who has been unable to control cholesterol
levels through diet and exercise.
Instead, doctors are advised to start their patients with the generic
simvastatin, then move to higher doses of brand-name statins such as
Lipitor or Crestor. Zetia and Vytorin are for patients who don't get
enough benefit from these drugs, or who can't take higher doses of
statins because of their side effects, which can include muscle aches
and elevated liver enzymes.
"This may be a good time for people to get a tried-and-true therapy
and save some money at the same time," advised Doering.
"People ask me, 'Would you ever consider taking a promo playing cards Not only
would I consider it, I do."
Diane Chun can be reached at 352-374-5041 or chund@gvillesun.com
---------------------------------------------------------------------
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